Supplement Stack Builder
Pre-Built Stacks by Goal
Seven curated supplement stacks, each designed around a specific health goal and built from real expert protocols. Every product links back to the influencers who recommend it, with budget and premium tier pricing.
Longevity Basics
Recommended by 5+ experts
The foundational stack that appears across nearly every longevity protocol. These are the supplements where experts overwhelmingly agree: start here before adding anything else.
Omega-3 Fish Oil (High EPA)
$15 – $45/mo
High-potency omega-3 fish oil supplement with elevated EPA content. Supports cardiovascular health, reduces systemic inflammation, and promotes healthy brain function and mood regulation.
Vitamin D3 (5000 IU)
$8 – $20/mo
High-potency vitamin D3 supplement providing 5000 IU per serving to support optimal blood levels. Essential for immune function, bone health, and mood regulation. One of the most widely recommended supplements among longevity researchers due to widespread deficiency.
Magnesium (Threonate/Glycinate)
$12 – $35/mo
Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.
Creatine Monohydrate
$10 – $25/mo
Pure creatine monohydrate, one of the most well-researched supplements in sports science. Supports muscle strength, power output, and emerging research suggests cognitive benefits. Safe for long-term daily use at 3-5 grams per day.
Vitamin K2 (MK-7)
$8 – $18/mo
Vitamin K2 in the MK-7 form supports proper calcium metabolism, directing calcium into bones and teeth while preventing arterial calcification. Works synergistically with vitamin D3 to optimize bone mineral density and cardiovascular health. Essential for activating proteins involved in blood coagulation and vascular protection.
Brain Performance
Nootropic & cognitive support
Targeted at neuroplasticity, memory, and mental clarity. Lion's mane stimulates nerve growth factor, omega-3s maintain neuronal membrane integrity, and creatine fuels the brain's high ATP demand.
Lion's Mane Mushroom Extract
$20 – $45/mo
Dual-extracted lion's mane mushroom (Hericium erinaceus) containing both hericenones and erinacines, compounds shown to stimulate nerve growth factor (NGF) production. Supports cognitive function, memory, and neuroplasticity. A staple in nootropic and longevity stacks for its unique neurotrophic properties.
Omega-3 Fish Oil (High EPA)
$15 – $45/mo
High-potency omega-3 fish oil supplement with elevated EPA content. Supports cardiovascular health, reduces systemic inflammation, and promotes healthy brain function and mood regulation.
Creatine Monohydrate
$10 – $25/mo
Pure creatine monohydrate, one of the most well-researched supplements in sports science. Supports muscle strength, power output, and emerging research suggests cognitive benefits. Safe for long-term daily use at 3-5 grams per day.
Magnesium (Threonate/Glycinate)
$12 – $35/mo
Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.
L-Theanine
$10 – $22/mo
An amino acid found naturally in green tea that promotes calm focus without drowsiness. L-theanine increases alpha brain wave activity, supporting relaxation and stress reduction. Often combined with magnesium and melatonin for improved sleep quality, or paired with caffeine for smooth, jitter-free mental clarity.
Gut Health
Microbiome & digestive support
A healthy gut microbiome is foundational to immune function, mood, and nutrient absorption. This stack combines probiotics with prebiotic and fermented food sources to cultivate microbial diversity.
Probiotics (Multi-Strain)
$15 – $50/mo
Multi-strain probiotic supplement containing diverse beneficial bacteria to support gut microbiome health. A balanced gut microbiome is linked to improved digestion, immune function, and mental well-being. Look for formulas with clinically studied strains and high CFU counts.
Fermented Foods (Kimchi, Sauerkraut, Kefir)
$20 – $40/mo
Naturally fermented foods rich in live beneficial bacteria to support gut microbiome diversity. Regular consumption of kimchi, sauerkraut, and kefir has been shown to reduce markers of systemic inflammation. A Stanford study found fermented foods increased microbial diversity more effectively than a high-fiber diet.
Bone Broth
$25 – $60/mo
Nutrient-dense broth made by simmering animal bones for extended periods. Rich in collagen, glycine, and minerals. Frequently recommended by Dr. Jason Fung as one of the best fasting aids — it provides electrolytes and a small amount of protein to ease hunger during extended fasts without significantly raising insulin.
Collagen Peptides
$20 – $45/mo
Hydrolyzed collagen peptides that support skin elasticity, joint health, and connective tissue repair. Easily dissolved in hot or cold liquids for convenient daily supplementation.
Digestive Enzymes
$15 – $35/mo
Digestive enzyme supplements contain a blend of proteases, lipases, and amylases that support the breakdown of proteins, fats, and carbohydrates. They can be especially helpful for individuals with reduced enzyme production due to aging, stress, or digestive conditions, improving nutrient absorption and reducing bloating.
Anti-Inflammation
Reduce chronic inflammation
Chronic low-grade inflammation accelerates aging and drives most chronic disease. This stack targets multiple inflammatory pathways through complementary mechanisms — from NF-kB inhibition to omega-3-mediated resolution.
Turmeric / Curcumin
$12 – $35/mo
Turmeric extract standardized for curcumin content, a potent anti-inflammatory compound. Supports joint health, reduces chronic inflammation, and may protect against age-related cognitive decline. Best absorbed when paired with piperine (black pepper extract) or in a liposomal formulation.
Omega-3 Fish Oil (High EPA)
$15 – $45/mo
High-potency omega-3 fish oil supplement with elevated EPA content. Supports cardiovascular health, reduces systemic inflammation, and promotes healthy brain function and mood regulation.
Sulforaphane / Broccoli Sprout Extract
$20 – $40/mo
Concentrated sulforaphane from broccoli sprout extract, a potent activator of the body's Nrf2 antioxidant pathway. Supports detoxification, reduces inflammation, and has been extensively studied for its cellular protective properties. Best absorbed when taken with a source of myrosinase.
Quercetin
$15 – $30/mo
Quercetin is a plant flavonoid with potent antioxidant and anti-inflammatory properties. Supports immune function, cardiovascular health, and has been studied as a senolytic agent that helps clear damaged senescent cells. Often combined with vitamin C or bromelain to enhance absorption.
Green Tea (Matcha)
$10 – $25/mo
High-quality matcha green tea powder rich in EGCG catechins and L-theanine. Provides calm, sustained energy while delivering powerful antioxidant and anti-inflammatory benefits. Regular green tea consumption is associated with reduced cardiovascular disease risk and improved metabolic health in population studies.
Energy & Mitochondria
Cellular energy production
Mitochondrial function declines with age, reducing cellular energy output. CoQ10 is essential for the electron transport chain, NAD+ precursors fuel sirtuin activity, and creatine acts as a phosphate energy buffer.
CoQ10 (Coenzyme Q10)
$20 – $50/mo
Coenzyme Q10 is a naturally occurring antioxidant that plays a critical role in mitochondrial energy production. CoQ10 levels decline with age, making supplementation increasingly relevant for supporting cardiovascular health, cellular energy, and overall vitality. The ubiquinol form offers superior bioavailability compared to ubiquinone.
NAD+ Precursor (NMN/NR)
$30 – $80/mo
NAD+ precursor supplement in NMN (nicotinamide mononucleotide) or NR (nicotinamide riboside) form. Supports cellular energy production and DNA repair by boosting NAD+ levels, which naturally decline with age. A cornerstone supplement in many longevity-focused protocols.
Creatine Monohydrate
$10 – $25/mo
Pure creatine monohydrate, one of the most well-researched supplements in sports science. Supports muscle strength, power output, and emerging research suggests cognitive benefits. Safe for long-term daily use at 3-5 grams per day.
Magnesium (Threonate/Glycinate)
$12 – $35/mo
Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.
Cordyceps Mushroom Extract
$18 – $40/mo
Concentrated cordyceps militaris mushroom extract standardized for cordycepin and adenosine content. Traditionally used to support endurance, oxygen utilization, and cellular energy production. Modern research suggests benefits for aerobic capacity and mitochondrial function.
Sleep Optimization
Deep, restorative sleep
Sleep is the single most impactful health behavior. Magnesium glycinate promotes GABA activity, glycine lowers core body temperature for sleep onset, and L-theanine induces calm alpha-wave brain states without sedation.
Magnesium (Threonate/Glycinate)
$12 – $35/mo
Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.
Melatonin (Low Dose)
$5 – $15/mo
Low-dose melatonin supplement to support natural circadian rhythm and sleep onset. Research suggests doses of 0.3-1 mg are often more effective than higher amounts for improving sleep quality. Also studied for its antioxidant properties and potential anti-aging benefits.
L-Theanine
$10 – $22/mo
An amino acid found naturally in green tea that promotes calm focus without drowsiness. L-theanine increases alpha brain wave activity, supporting relaxation and stress reduction. Often combined with magnesium and melatonin for improved sleep quality, or paired with caffeine for smooth, jitter-free mental clarity.
Glycine
$10 – $20/mo
Glycine is the simplest amino acid and a key building block for collagen, glutathione, and creatine. Supplementing with glycine supports sleep quality, joint health, and detoxification. Research suggests 3-5 grams before bed can improve sleep onset and next-day cognitive performance.
Fasting Support
Sustain energy while fasting
Fasting triggers autophagy and metabolic flexibility, but electrolyte depletion and energy dips can derail the practice. This stack maintains mineral balance and provides clean energy without breaking your fast.
Electrolyte Mix
$15 – $35/mo
Balanced electrolyte mix containing sodium, potassium, and magnesium to support hydration and cellular function. Essential for maintaining energy levels, muscle function, and cognitive performance, especially during fasting or exercise. Sugar-free formulas are preferred in longevity protocols.
Green Tea (Matcha)
$10 – $25/mo
High-quality matcha green tea powder rich in EGCG catechins and L-theanine. Provides calm, sustained energy while delivering powerful antioxidant and anti-inflammatory benefits. Regular green tea consumption is associated with reduced cardiovascular disease risk and improved metabolic health in population studies.
Bone Broth
$25 – $60/mo
Nutrient-dense broth made by simmering animal bones for extended periods. Rich in collagen, glycine, and minerals. Frequently recommended by Dr. Jason Fung as one of the best fasting aids — it provides electrolytes and a small amount of protein to ease hunger during extended fasts without significantly raising insulin.
Black Coffee
$15 – $40/mo
High-quality black coffee, one of the most widely recommended beverages during intermittent fasting. Contains caffeine and chlorogenic acid, which may increase metabolic rate and fat oxidation. Dr. Jason Fung considers black coffee an excellent fasting companion — it suppresses appetite, does not stimulate insulin, and may enhance the metabolic benefits of fasting.
Magnesium (Threonate/Glycinate)
$12 – $35/mo
Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.
Disclaimer: Monthly cost estimates are approximate ranges based on typical retail pricing at the time of writing. Actual costs vary by brand, dosage, and retailer. “Budget” reflects affordable, well-reviewed options; “Premium” reflects clinical-grade or influencer-preferred brands. Always consult a qualified healthcare provider before starting any supplement regimen.
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