Ben Greenfield vs Valter Longo

Compare Ben Greenfield's protocol (Exercise Physiologist & Biohacker) with Valter Longo's approach (Longevity Researcher & USC Professor). Greenfield emphasizes longevity and biohacking, while Longo focuses on fasting and longevity. Both recommend Omega-3 Fish Oil (High EPA), Vitamin D3 (5000 IU).

Side-by-Side Comparison

CategoryBen GreenfieldValter Longo
TitleExercise Physiologist & BiohackerLongevity Researcher & USC Professor
Focus Areas
longevitybiohackingsupplementsancestral healthfitnessadaptogens
fastinglongevityresearchdiet
Total Products153
Shared Products2 products in common
ProtocolA comprehensive longevity protocol blending ancestral health practices with advanced biohacking — including targeted supplementation, cold and heat exposure, metabolic flexibility training, and a deep functional mushroom and adaptogen stack.A research-backed fasting protocol centered on the fasting-mimicking diet (FMD), emphasizing periodic caloric restriction cycles to promote cellular regeneration and reduce biological age.

What They Agree On

Both Ben Greenfield and Valter Longo include these 2 products in their protocols — a signal of strong evidence and broad expert consensus.

Omega-3 Fish Oil (High EPA)

High-potency omega-3 fish oil supplement with elevated EPA content. Supports cardiovascular health, reduces systemic inflammation, and promotes healthy brain function and mood regulation.

Omega-3 Fish Oil (High EPA)

supplements

Vitamin D3 (5000 IU)

High-potency vitamin D3 supplement providing 5000 IU per serving to support optimal blood levels. Essential for immune function, bone health, and mood regulation. One of the most widely recommended supplements among longevity researchers due to widespread deficiency.

Vitamin D3 (5000 IU)

supplements

Where They Differ

These products are unique to one protocol — reflecting each expert's distinct philosophy, research focus, and priorities.

Ben Greenfield

Only in Ben Greenfield's Protocol

Creatine Monohydrate

Pure creatine monohydrate, one of the most well-researched supplements in sports science. Supports muscle strength, power output, and emerging research suggests cognitive benefits. Safe for long-term daily use at 3-5 grams per day.

Magnesium (Threonate/Glycinate)

Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.

Electrolyte Mix

Balanced electrolyte mix containing sodium, potassium, and magnesium to support hydration and cellular function. Essential for maintaining energy levels, muscle function, and cognitive performance, especially during fasting or exercise. Sugar-free formulas are preferred in longevity protocols.

Collagen Peptides

Hydrolyzed collagen peptides that support skin elasticity, joint health, and connective tissue repair. Easily dissolved in hot or cold liquids for convenient daily supplementation.

Ashwagandha (KSM-66)

KSM-66 ashwagandha root extract, the most clinically studied form of this traditional adaptogenic herb. Supports healthy cortisol levels, reduces perceived stress, and may improve sleep quality and exercise recovery. Widely used in longevity protocols for its effects on hormonal balance and resilience to chronic stress.

Cordyceps Mushroom Extract

Concentrated cordyceps militaris mushroom extract standardized for cordycepin and adenosine content. Traditionally used to support endurance, oxygen utilization, and cellular energy production. Modern research suggests benefits for aerobic capacity and mitochondrial function.

Lion's Mane Mushroom Extract

Dual-extracted lion's mane mushroom (Hericium erinaceus) containing both hericenones and erinacines, compounds shown to stimulate nerve growth factor (NGF) production. Supports cognitive function, memory, and neuroplasticity. A staple in nootropic and longevity stacks for its unique neurotrophic properties.

Exogenous Ketones (BHB Salts)

Beta-hydroxybutyrate (BHB) salt supplement that rapidly elevates blood ketone levels without requiring extended fasting or strict carbohydrate restriction. Supports mental clarity, sustained energy, and may enhance endurance performance. Used as a bridging tool for metabolic flexibility in biohacking protocols.

Bovine Colostrum

Grass-fed bovine colostrum rich in immunoglobulins, lactoferrin, and growth factors. Supports gut barrier integrity, immune function, and recovery from intense exercise. Increasingly popular in longevity circles for its ability to reduce intestinal permeability and modulate inflammation.

Essential Amino Acids (EAAs)

Complete essential amino acid formula providing all nine EAAs in research-backed ratios. Supports muscle protein synthesis, recovery, and lean body composition with minimal caloric load. Preferred over BCAAs alone because the full EAA profile is required for complete protein turnover and tissue repair.

Molecular Hydrogen Tablets

Effervescent tablets that dissolve in water to produce molecular hydrogen (H2) gas. Molecular hydrogen acts as a selective antioxidant, neutralizing hydroxyl radicals without disrupting beneficial reactive oxygen species. Emerging research suggests benefits for exercise recovery, inflammation reduction, and mitochondrial health.

Quercetin

Quercetin is a plant flavonoid with potent antioxidant and anti-inflammatory properties. Supports immune function, cardiovascular health, and has been studied as a senolytic agent that helps clear damaged senescent cells. Often combined with vitamin C or bromelain to enhance absorption.

Glutathione (Liposomal)

Liposomal glutathione supplement for enhanced absorption of the body's master antioxidant. Glutathione plays a critical role in detoxification, immune support, and protecting cells from oxidative stress. Liposomal delivery bypasses digestive breakdown for greater bioavailability.

Valter Longo

Only in Valter Longo's Protocol

Extra Virgin Olive Oil

Cold-pressed extra virgin olive oil, a cornerstone of Mediterranean and longevity diets. Rich in polyphenols and oleic acid.

Product Comparison

ProductBen GreenfieldValter Longo
Omega-3 Fish Oil (High EPA)RecommendedRecommended
Vitamin D3 (5000 IU)RecommendedRecommended
Creatine MonohydrateRecommended---
Magnesium (Threonate/Glycinate)Recommended---
Electrolyte MixRecommended---
Collagen PeptidesRecommended---
Ashwagandha (KSM-66)Recommended---
Extra Virgin Olive Oil---Recommended

Frequently Asked Questions

What is the difference between Ben Greenfield's and Valter Longo's protocols?

Compare Ben Greenfield's protocol (Exercise Physiologist & Biohacker) with Valter Longo's approach (Longevity Researcher & USC Professor). Greenfield emphasizes longevity and biohacking, while Longo focuses on fasting and longevity. Both recommend Omega-3 Fish Oil (High EPA), Vitamin D3 (5000 IU).

What do Ben Greenfield and Valter Longo both recommend?

Both experts recommend Omega-3 Fish Oil (High EPA), Vitamin D3 (5000 IU). These shared recommendations carry extra weight because they represent consensus across two independent, well-informed approaches to longevity.

Which protocol is better for beginners?

Both protocols can be adapted for beginners. Start with the fundamentals both experts agree on — Omega-3 Fish Oil (High EPA), Vitamin D3 (5000 IU) — then gradually explore the unique elements of each protocol based on your specific health goals and budget.

All Products From Both Protocols

Omega-3 Fish Oil (High EPA)

supplements

Vitamin D3 (5000 IU)

supplements

Creatine Monohydrate

supplements

Magnesium (Threonate/Glycinate)

supplements

Electrolyte Mix

supplements

Collagen Peptides

supplements

Ashwagandha (KSM-66)

supplements

Cordyceps Mushroom Extract

supplements

Lion's Mane Mushroom Extract

supplements

Exogenous Ketones (BHB Salts)

supplements

Bovine Colostrum

supplements

Essential Amino Acids (EAAs)

supplements

Molecular Hydrogen Tablets

supplements

Quercetin

supplements

Glutathione (Liposomal)

supplements

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Extra Virgin Olive Oil

foods

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