Ben Greenfield vs David Sinclair

Creatine Monohydrate

Pure creatine monohydrate, one of the most well-researched supplements in sports science. Supports muscle strength, power output, and emerging research suggests cognitive benefits. Safe for long-term daily use at 3-5 grams per day.

Magnesium (Threonate/Glycinate)

Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.

Electrolyte Mix

Balanced electrolyte mix containing sodium, potassium, and magnesium to support hydration and cellular function. Essential for maintaining energy levels, muscle function, and cognitive performance, especially during fasting or exercise. Sugar-free formulas are preferred in longevity protocols.

Collagen Peptides

Hydrolyzed collagen peptides that support skin elasticity, joint health, and connective tissue repair. Easily dissolved in hot or cold liquids for convenient daily supplementation.

Ashwagandha (KSM-66)

KSM-66 ashwagandha root extract, the most clinically studied form of this traditional adaptogenic herb. Supports healthy cortisol levels, reduces perceived stress, and may improve sleep quality and exercise recovery. Widely used in longevity protocols for its effects on hormonal balance and resilience to chronic stress.

Cordyceps Mushroom Extract

Concentrated cordyceps militaris mushroom extract standardized for cordycepin and adenosine content. Traditionally used to support endurance, oxygen utilization, and cellular energy production. Modern research suggests benefits for aerobic capacity and mitochondrial function.

Lion's Mane Mushroom Extract

Dual-extracted lion's mane mushroom (Hericium erinaceus) containing both hericenones and erinacines, compounds shown to stimulate nerve growth factor (NGF) production. Supports cognitive function, memory, and neuroplasticity. A staple in nootropic and longevity stacks for its unique neurotrophic properties.

Exogenous Ketones (BHB Salts)

Beta-hydroxybutyrate (BHB) salt supplement that rapidly elevates blood ketone levels without requiring extended fasting or strict carbohydrate restriction. Supports mental clarity, sustained energy, and may enhance endurance performance. Used as a bridging tool for metabolic flexibility in biohacking protocols.

Bovine Colostrum

Grass-fed bovine colostrum rich in immunoglobulins, lactoferrin, and growth factors. Supports gut barrier integrity, immune function, and recovery from intense exercise. Increasingly popular in longevity circles for its ability to reduce intestinal permeability and modulate inflammation.

Essential Amino Acids (EAAs)

Complete essential amino acid formula providing all nine EAAs in research-backed ratios. Supports muscle protein synthesis, recovery, and lean body composition with minimal caloric load. Preferred over BCAAs alone because the full EAA profile is required for complete protein turnover and tissue repair.

Molecular Hydrogen Tablets

Effervescent tablets that dissolve in water to produce molecular hydrogen (H2) gas. Molecular hydrogen acts as a selective antioxidant, neutralizing hydroxyl radicals without disrupting beneficial reactive oxygen species. Emerging research suggests benefits for exercise recovery, inflammation reduction, and mitochondrial health.

Quercetin

Quercetin is a plant flavonoid with potent antioxidant and anti-inflammatory properties. Supports immune function, cardiovascular health, and has been studied as a senolytic agent that helps clear damaged senescent cells. Often combined with vitamin C or bromelain to enhance absorption.

Glutathione (Liposomal)

Liposomal glutathione supplement for enhanced absorption of the body's master antioxidant. Glutathione plays a critical role in detoxification, immune support, and protecting cells from oxidative stress. Liposomal delivery bypasses digestive breakdown for greater bioavailability.

NAD+ Precursor (NMN/NR)

NAD+ precursor supplement in NMN (nicotinamide mononucleotide) or NR (nicotinamide riboside) form. Supports cellular energy production and DNA repair by boosting NAD+ levels, which naturally decline with age. A cornerstone supplement in many longevity-focused protocols.

Extra Virgin Olive Oil

Cold-pressed extra virgin olive oil, a cornerstone of Mediterranean and longevity diets. Rich in polyphenols and oleic acid.

Green Tea (Matcha)

High-quality matcha green tea powder rich in EGCG catechins and L-theanine. Provides calm, sustained energy while delivering powerful antioxidant and anti-inflammatory benefits. Regular green tea consumption is associated with reduced cardiovascular disease risk and improved metabolic health in population studies.