Thomas DeLauer vs Dave Asprey
Compare Thomas DeLauer's keto-fasting protocol with Dave Asprey's biohacking approach. Both champion ketosis and intermittent fasting as core health strategies — DeLauer focuses on cyclical keto with evidence-backed supplementation and gut health, while Asprey pioneered Bulletproof Coffee, MCT oil, and a technology-forward biohacking framework. DeLauer is more research-citation-heavy and supplement-diverse; Asprey leans more into biohacking devices and cognitive performance optimization.

Thomas DeLauer
Keto & Fasting Expert, Performance Coach
A comprehensive keto-fasting protocol combining cyclical ketogenic nutrition, strategic intermittent fasting, and an extensive evidence-informed supplement stack designed for fat loss, mental clarity, and sustained metabolic performance.
12 products in protocol

Dave Asprey
Biohacker & Bulletproof Founder
A biohacking-focused protocol combining bulletproof coffee, intermittent fasting, targeted supplementation, and technology-assisted health optimization for cognitive performance and longevity.
14 products in protocol
Side-by-Side Comparison
| Category | Thomas DeLauer | Dave Asprey |
|---|---|---|
| Title | Keto & Fasting Expert, Performance Coach | Biohacker & Bulletproof Founder |
| Focus Areas | ketofastingfat losssupplementsgut healthperformancenutrition | biohackingcognitive performancesupplementsfasting |
| Total Products | 12 | 4 |
| Shared Products | 3 products in common | |
| Protocol | A comprehensive keto-fasting protocol combining cyclical ketogenic nutrition, strategic intermittent fasting, and an extensive evidence-informed supplement stack designed for fat loss, mental clarity, and sustained metabolic performance. | A biohacking-focused protocol combining bulletproof coffee, intermittent fasting, targeted supplementation, and technology-assisted health optimization for cognitive performance and longevity. |
What They Agree On
Both Thomas DeLauer and Dave Asprey include these 3 products in their protocols — a signal of strong evidence and broad expert consensus.
Magnesium (Threonate/Glycinate)
Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.
Magnesium (Threonate/Glycinate)
supplements
Collagen Peptides
Hydrolyzed collagen peptides that support skin elasticity, joint health, and connective tissue repair. Easily dissolved in hot or cold liquids for convenient daily supplementation.
Collagen Peptides
supplements
Vitamin D3 (5000 IU)
High-potency vitamin D3 supplement providing 5000 IU per serving to support optimal blood levels. Essential for immune function, bone health, and mood regulation. One of the most widely recommended supplements among longevity researchers due to widespread deficiency.
Vitamin D3 (5000 IU)
supplements
Where They Differ
These products are unique to one protocol — reflecting each expert's distinct philosophy, research focus, and priorities.

Only in Thomas DeLauer's Protocol
Omega-3 Fish Oil (High EPA)
High-potency omega-3 fish oil supplement with elevated EPA content. Supports cardiovascular health, reduces systemic inflammation, and promotes healthy brain function and mood regulation.
Creatine Monohydrate
Pure creatine monohydrate, one of the most well-researched supplements in sports science. Supports muscle strength, power output, and emerging research suggests cognitive benefits. Safe for long-term daily use at 3-5 grams per day.
Probiotics (Multi-Strain)
Multi-strain probiotic supplement containing diverse beneficial bacteria to support gut microbiome health. A balanced gut microbiome is linked to improved digestion, immune function, and mental well-being. Look for formulas with clinically studied strains and high CFU counts.
Electrolyte Mix
Balanced electrolyte mix containing sodium, potassium, and magnesium to support hydration and cellular function. Essential for maintaining energy levels, muscle function, and cognitive performance, especially during fasting or exercise. Sugar-free formulas are preferred in longevity protocols.
Green Tea (Matcha)
High-quality matcha green tea powder rich in EGCG catechins and L-theanine. Provides calm, sustained energy while delivering powerful antioxidant and anti-inflammatory benefits. Regular green tea consumption is associated with reduced cardiovascular disease risk and improved metabolic health in population studies.
Apple Cider Vinegar
Raw, unfiltered apple cider vinegar with the 'mother' culture. Research suggests it may help reduce blood sugar spikes after meals by slowing gastric emptying. Dr. Jason Fung recommends it as a fasting aid — a tablespoon or two in water can help suppress hunger and stimulate digestion when breaking a fast.
MCT Oil
Medium-chain triglyceride (MCT) oil is a concentrated fat supplement derived from coconut or palm kernel oil. MCTs are rapidly absorbed and converted to ketones in the liver, providing quick energy for the brain and body. Popular among fasting and keto practitioners for sustaining energy without spiking insulin.
Bone Broth
Nutrient-dense broth made by simmering animal bones for extended periods. Rich in collagen, glycine, and minerals. Frequently recommended by Dr. Jason Fung as one of the best fasting aids — it provides electrolytes and a small amount of protein to ease hunger during extended fasts without significantly raising insulin.
CoQ10 (Coenzyme Q10)
Coenzyme Q10 is a naturally occurring antioxidant that plays a critical role in mitochondrial energy production. CoQ10 levels decline with age, making supplementation increasingly relevant for supporting cardiovascular health, cellular energy, and overall vitality. The ubiquinol form offers superior bioavailability compared to ubiquinone.
Lion's Mane Mushroom Extract
Dual-extracted lion's mane mushroom (Hericium erinaceus) containing both hericenones and erinacines, compounds shown to stimulate nerve growth factor (NGF) production. Supports cognitive function, memory, and neuroplasticity. A staple in nootropic and longevity stacks for its unique neurotrophic properties.
Dark Chocolate (85%+ Cacao)
High-cacao dark chocolate rich in flavanols and antioxidants. Studies link regular consumption to improved cardiovascular health, lower blood pressure, and enhanced cognitive function.

Only in Dave Asprey's Protocol
Extra Virgin Olive Oil
Cold-pressed extra virgin olive oil, a cornerstone of Mediterranean and longevity diets. Rich in polyphenols and oleic acid.
Product Comparison
| Product | Thomas DeLauer | Dave Asprey |
|---|---|---|
| Magnesium (Threonate/Glycinate) | Recommended | Recommended |
| Collagen Peptides | Recommended | Recommended |
| Vitamin D3 (5000 IU) | Recommended | Recommended |
| Omega-3 Fish Oil (High EPA) | Recommended | --- |
| Creatine Monohydrate | Recommended | --- |
| Probiotics (Multi-Strain) | Recommended | --- |
| Electrolyte Mix | Recommended | --- |
| Green Tea (Matcha) | Recommended | --- |
| Extra Virgin Olive Oil | --- | Recommended |
Frequently Asked Questions
What is the difference between Thomas DeLauer's and Dave Asprey's protocols?
Compare Thomas DeLauer's keto-fasting protocol with Dave Asprey's biohacking approach. Both champion ketosis and intermittent fasting as core health strategies — DeLauer focuses on cyclical keto with evidence-backed supplementation and gut health, while Asprey pioneered Bulletproof Coffee, MCT oil, and a technology-forward biohacking framework. DeLauer is more research-citation-heavy and supplement-diverse; Asprey leans more into biohacking devices and cognitive performance optimization.
What do Thomas DeLauer and Dave Asprey both recommend?
Both experts recommend Magnesium (Threonate/Glycinate), Collagen Peptides, Vitamin D3 (5000 IU). These shared recommendations carry extra weight because they represent consensus across two independent, well-informed approaches to longevity.
Which protocol is better for beginners?
Both protocols can be adapted for beginners. Start with the fundamentals both experts agree on — Magnesium (Threonate/Glycinate), Collagen Peptides, Vitamin D3 (5000 IU) — then gradually explore the unique elements of each protocol based on your specific health goals and budget.
All Products From Both Protocols
Magnesium (Threonate/Glycinate)
supplements
Collagen Peptides
supplements
Vitamin D3 (5000 IU)
supplements
Omega-3 Fish Oil (High EPA)
supplements
Creatine Monohydrate
supplements
Probiotics (Multi-Strain)
supplements
Electrolyte Mix
supplements
Green Tea (Matcha)
foods
Apple Cider Vinegar
foods
MCT Oil
supplements
Bone Broth
foods
CoQ10 (Coenzyme Q10)
supplements
Lion's Mane Mushroom Extract
supplements
Dark Chocolate (85%+ Cacao)
foods
Extra Virgin Olive Oil
foods
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