Mike Mutzel vs Layne Norton

Berberine

Berberine is a bioactive compound extracted from several plants including barberry and goldenseal. Research shows it can significantly improve blood sugar regulation, lipid profiles, and gut health. Often compared to metformin for its glucose-lowering effects, berberine activates AMPK, a key enzyme in metabolic regulation.

Zinc (Picolinate)

Zinc picolinate supplement offering superior absorption compared to other zinc forms. Supports immune function, hormone production, and wound healing. Important for maintaining testosterone levels and thyroid health, particularly in those with dietary deficiencies.

Melatonin (Low Dose)

Low-dose melatonin supplement to support natural circadian rhythm and sleep onset. Research suggests doses of 0.3-1 mg are often more effective than higher amounts for improving sleep quality. Also studied for its antioxidant properties and potential anti-aging benefits.

Taurine

Taurine is a conditionally essential amino acid concentrated in the brain, heart, and muscles. A landmark 2023 study in Science found that taurine levels decline with age and that supplementation extended lifespan in animal models. It supports cardiovascular function, mitochondrial health, and exercise performance.

Iodine Supplement

Iodine is an essential trace mineral required for thyroid hormone production, which regulates metabolism, energy, and body temperature. Deficiency is widespread globally and can lead to hypothyroidism, fatigue, and cognitive impairment. Seaweed, fish, and iodized salt are dietary sources, but supplementation ensures adequate intake.

Inositol (Myo-Inositol)

Inositol is a carbocyclic sugar involved in insulin signaling, neurotransmitter function, and lipid metabolism. Myo-inositol supplementation has shown benefits for insulin sensitivity, hormonal balance, anxiety reduction, and sleep quality. It is particularly well-studied for metabolic syndrome and PCOS support.

Whey Protein Isolate

Whey protein isolate is a fast-absorbing, complete protein derived from milk that delivers all essential amino acids with minimal fat and lactose. It is one of the most well-studied supplements for supporting muscle protein synthesis, recovery from exercise, and preservation of lean mass during caloric restriction.

Black Coffee

High-quality black coffee, one of the most widely recommended beverages during intermittent fasting. Contains caffeine and chlorogenic acid, which may increase metabolic rate and fat oxidation. Dr. Jason Fung considers black coffee an excellent fasting companion — it suppresses appetite, does not stimulate insulin, and may enhance the metabolic benefits of fasting.

Pasture-Raised Eggs

Pasture-raised eggs are a nutrient-dense whole food providing complete protein, healthy fats, choline, and fat-soluble vitamins. Among protein sources, eggs produce one of the lowest insulin responses — making them a preferred choice in Dr. Jason Fung's protocol for meals that support metabolic health and stable blood sugar.

Collagen Protein

Collagen protein supplements provide the specific amino acids — glycine, proline, and hydroxyproline — needed to support skin elasticity, joint cartilage, and connective tissue repair. While similar to collagen peptides, collagen protein powders are often formulated for use as a protein source in smoothies and baking.

Vitamin C

High-quality vitamin C supplement supporting immune function, collagen synthesis, and antioxidant defense. Essential for tissue repair and iron absorption. Liposomal forms offer enhanced bioavailability compared to standard ascorbic acid.