Mark Hyman vs Bryan Johnson

Omega-3 Fish Oil (High EPA)

High-potency omega-3 fish oil supplement with elevated EPA content. Supports cardiovascular health, reduces systemic inflammation, and promotes healthy brain function and mood regulation.

Vitamin D3 (5000 IU)

High-potency vitamin D3 supplement providing 5000 IU per serving to support optimal blood levels. Essential for immune function, bone health, and mood regulation. One of the most widely recommended supplements among longevity researchers due to widespread deficiency.

Magnesium (Threonate/Glycinate)

Highly bioavailable magnesium in threonate or glycinate form for superior absorption. Supports deep sleep quality, cognitive function, and nervous system relaxation. Magnesium threonate is particularly valued for its ability to cross the blood-brain barrier.

Probiotics (Multi-Strain)

Multi-strain probiotic supplement containing diverse beneficial bacteria to support gut microbiome health. A balanced gut microbiome is linked to improved digestion, immune function, and mental well-being. Look for formulas with clinically studied strains and high CFU counts.

Glutathione (Liposomal)

Liposomal glutathione supplement for enhanced absorption of the body's master antioxidant. Glutathione plays a critical role in detoxification, immune support, and protecting cells from oxidative stress. Liposomal delivery bypasses digestive breakdown for greater bioavailability.

Vitamin C

High-quality vitamin C supplement supporting immune function, collagen synthesis, and antioxidant defense. Essential for tissue repair and iron absorption. Liposomal forms offer enhanced bioavailability compared to standard ascorbic acid.

Zinc (Picolinate)

Zinc picolinate supplement offering superior absorption compared to other zinc forms. Supports immune function, hormone production, and wound healing. Important for maintaining testosterone levels and thyroid health, particularly in those with dietary deficiencies.

Green Tea (Matcha)

High-quality matcha green tea powder rich in EGCG catechins and L-theanine. Provides calm, sustained energy while delivering powerful antioxidant and anti-inflammatory benefits. Regular green tea consumption is associated with reduced cardiovascular disease risk and improved metabolic health in population studies.

Turmeric / Curcumin

Turmeric extract standardized for curcumin content, a potent anti-inflammatory compound. Supports joint health, reduces chronic inflammation, and may protect against age-related cognitive decline. Best absorbed when paired with piperine (black pepper extract) or in a liposomal formulation.

Extra Virgin Olive Oil

Cold-pressed extra virgin olive oil, a cornerstone of Mediterranean and longevity diets. Rich in polyphenols and oleic acid.

Dark Chocolate (85%+ Cacao)

High-cacao dark chocolate rich in flavanols and antioxidants. Studies link regular consumption to improved cardiovascular health, lower blood pressure, and enhanced cognitive function.

Raw Macadamia Nuts

Raw, unsalted macadamia nuts prized for their high monounsaturated fat content and low omega-6 to omega-3 ratio. A favored fat source in longevity-focused diets for their anti-inflammatory profile.

Collagen Peptides

Hydrolyzed collagen peptides that support skin elasticity, joint health, and connective tissue repair. Easily dissolved in hot or cold liquids for convenient daily supplementation.

Organic Blueberry Powder

Freeze-dried organic blueberry powder concentrated in anthocyanins and antioxidants. Supports cerebrovascular health, cognitive function, and cellular protection against oxidative stress.